Mac and Cheese Meatloaf Casserole

A Comfort Food Fusion That’s Pure Magic
If you’ve ever found yourself torn between craving classic meatloaf and creamy, cheesy mac and cheese — this dish is your dream come true. Mac and Cheese Meatloaf Casserole takes two beloved comfort foods and fuses them into one hearty, soul-warming dinner. It’s the kind of meal that brings everyone to the table fast and keeps them coming back for seconds.
This recipe is rich, nostalgic, and ridiculously satisfying. Imagine tender, juicy meatloaf at the base — seasoned just right and smothered with a tangy layer of ketchup — then topped with a golden blanket of creamy macaroni and cheese. Finally, it’s finished with a bubbling crown of melted cheddar that ties everything together in a warm, cheesy embrace.
Whether you’re cooking for a weeknight family dinner, a weekend potluck, or simply treating yourself after a long day, this casserole guarantees pure comfort in every bite.
Mac and Cheese Meatloaf Casserole Recipe
Ingredients:
- 1½ lbs ground beef
- 1 egg
- ½ cup breadcrumbs
- ½ cup milk
- 1 tsp garlic powder
- 1 tsp onion powder
- ½ tsp salt
- ½ tsp pepper
- 1 cup ketchup (½ for mixture, ½ for topping)
- 3 cups prepared mac and cheese (homemade or boxed)
- 1½ cups shredded cheddar cheese
Instructions:
- Preheat & Prepare:
Preheat your oven to 350°F (175°C). Lightly grease a 9×13-inch baking dish to prevent sticking. - Mix the Meatloaf Base:
In a large bowl, combine the ground beef, egg, breadcrumbs, milk, garlic powder, onion powder, salt, pepper, and ½ cup ketchup. Mix gently with your hands or a spoon until everything is well combined, but don’t overmix — this helps keep the meatloaf tender. - Shape & Bake the Meatloaf:
Press the meat mixture evenly into the bottom of the baking dish to form a solid meatloaf layer. Spread the remaining ½ cup of ketchup over the top to create a flavorful glaze. Bake uncovered for 25–30 minutes, or until the meatloaf is almost fully cooked through. - Add the Mac & Cheese:
Remove the dish from the oven. Spread your prepared mac and cheese evenly over the top of the meatloaf layer. Then sprinkle the shredded cheddar cheese over the mac for an extra cheesy finish. - Final Bake:
Return the dish to the oven and bake for an additional 10–15 minutes, or until the cheese is melted, bubbly, and lightly golden. - Serve & Enjoy:
Let the casserole rest for a few minutes before slicing. Serve warm and watch it disappear fast!
Quick Tip: For a fun twist, sprinkle crispy bacon bits or crunchy French-fried onions on top just before serving. The extra texture takes this dish from comforting to unforgettable.
Why This Recipe Works
This recipe combines the best of both worlds — the savory, juicy depth of classic meatloaf and the creamy, cheesy indulgence of mac and cheese. The meatloaf base provides a rich, hearty flavor that balances beautifully with the mild creaminess of the mac. The final layer of melted cheddar ties everything together with a golden, gooey finish that makes every bite melt in your mouth.
It’s also incredibly easy to make — no complicated steps, no fancy ingredients. Just wholesome, classic flavors layered in one comforting casserole dish.
Serving Ideas
Pair this dish with a crisp green salad or roasted veggies to balance out the richness. Garlic bread or dinner rolls also make the perfect companion for scooping up every bit of cheesy goodness.
If you’re meal prepping, this casserole reheats beautifully — simply cover and refrigerate leftovers for up to 3 days, or freeze for up to 2 months.
The Comfort of Home in Every Bite
There’s something nostalgic about the combination of meatloaf and mac and cheese. It feels like a cozy Sunday dinner, the kind that brings the whole family together. Mac and Cheese Meatloaf Casserole is more than a meal — it’s a memory in the making, the kind of recipe that warms the soul and fills your kitchen with irresistible aromas.
So the next time you’re craving comfort food, skip the takeout and bake up this classic-meets-creamy masterpiece. It’s hearty, flavorful, and guaranteed to become a family favorite.




